Preheat your oven to 400°F.
In a small bowl, mix together the hot honey, olive oil, garlic powder, onion powder, smoked paprika, salt, black pepper, apple cider vinegar, and Dijon mustard until well combined.
Place the chicken breasts in a baking dish and pour the honey mixture over the chicken, ensuring each piece is well coated.
Bake in the preheated oven for 25-30 minutes, or until the chicken is cooked through and reaches an internal temperature of 165°F.
For a caramelized finish, broil the chicken for an additional 2-3 minutes at the end of baking.
Remove from the oven and let the chicken rest for 5 minutes before slicing and serving.